Ariana Boswell

All articles by Ariana Boswell

• Review calls for more long-term research on second-line therapies for PBC

  A recent study compares the mechanisms and safety profiles of a number of alternatives to ursodeoxycholic acid in patients with PBC.

• Lack of response to obeticholic acid linked to adverse events in PBC

  A recent study found that patients with PBC who do not respond to OCA within one year may have a higher risk of adverse effects.

• Study examines mechanism of obeticholic acid-mediated liver injury

  When researchers administered obeticholic acid to mice with liver disease, they released high levels of the inflammatory protein HMGB1.

• Study finds elevated BMI linked to higher risk of PBC

  A recent study utilized genetic markers demonstrate that individuals with higher BMI may have a higher risk of developing PBC.

• Rare Disease Day: Why it matters and how to get involved

  Rare Disease Day 2025 aims to uplift the rare disease community and promote greater awareness.

• PBC treatment roundup: Recent approvals and current options

  The U.S. recently approved new drugs to treat PBC, adding to several already in use to treat the symptoms and slow progress of the disease.